Another good free application to prevent unauthorized use of USB ports on your network. USB blocker is a free product of NetWrix (Microsoft Gold Certified Partner) corporation.
USB blocker comes in handy, especially, for organizations to control the use of confidential information, secure their network and comply with regulatory requirements. You can use this freeware to block all USB ports on the network easily. Using this tool you can prevent unauthorized use of removable media that connects to your computer USB ports, for example, USB drives, portable media players, and more.
Another advantage of this tool is simplicity, you can finish configuring USB Blocker with a couple of clicks. The program couldn't be much simpler to use. You can include or exclude any computer from block USB devices list easily.